For the treatment and control of internal parasitosis (produced by adult and immature forms of hematophagous and non-hematophagous gastrointestinal nematodes, lung nematodes and eye nematodes) and external parasitosis (lice, scabies, flies, oestrosis and cavity myiasis, among others). The association of ivermectin and closantel has demonstrated an additive effect and prolonged permanence in plasma.